American actor Eric Dane, recognized for his role in the television series 'Grey's Anatomy,' died yesterday Thursday at the age of 53 after battling amyotrophic lateral sclerosis.

Dane passed away nearly a year after publicly disclosing his ALS diagnosis, a neurodegenerative disease that progressively deteriorates muscle functions, according to People magazine.

His family confirmed the death through a statement noting that the actor died surrounded by his loved ones after "a brave battle" against the disease, according to the same source.

"He spent his final days surrounded by dear friends, his devoted wife, and his two beautiful daughters, Billie and Georgia, who were the center of his life," his representatives said in a statement released by THR.

"Eric became a passionate advocate for ALS awareness and research, determined to make a difference for those facing the same struggle," the statement read. "He will be deeply missed and always lovingly remembered. Eric adored his fans and is eternally grateful for the outpouring of love and support he has received," they added.

The performer achieved international fame for his role as Dr. Mark Sloan, known as "McSteamy," on Grey's Anatomy, where he became one of the most popular characters on the ABC medical drama.

His participation in the series consolidated his career in American television and positioned him as one of the most recognizable faces of the format in the 2000s.

Following his departure from the medical drama, Dane continued his trajectory in high-profile television productions, such as the series 'The Last Ship,' where he assumed a leading role, and more recently in 'Euphoria,' in which he portrayed Cal Jacobs.

In recent months, the actor had shown visible physical deterioration, although he maintained messages of strength and support for ALS research until his last public appearances.

Hollywood actors and directors have paid tribute in recent hours to the late actor.

"The Franklin Strip fantasy football league will miss Mr. Eric Dane. We know he'll be watching us from the booth. We miss you, friend. Let's keep fighting to solve ALS," actor Ashton Kutcher wrote on social media, mentioning the private celebrity football league in which both participated.

"I am heartbroken by the loss of our dear friend Eric. Working with him was an honor. Being his friend was a gift. Eric's family is in our prayers. May his memory be a blessing," said Sam Levinson, the creator of 'Euphoria,' in a statement released by The Hollywood Reporter (THR).

The official Instagram accounts of this series, which will soon premiere its third season, and its distributor HBO Max, also acknowledged the artist's passing.

"We are deeply saddened by the news of Eric Dane's passing. He was incredibly talented and HBO was fortunate to have worked with him on three seasons of 'Euphoria.' Our thoughts are with his loved ones during this difficult time," read the message issued by the popular series, also reproduced by HBO Max.

Michael Grassi, creator of 'Brilliant Minds,' the series in which the actor played one of his last roles as a firefighter with ALS, said working with Dane was "the greatest honor of my career."

"Eric was a television icon who lit up our screens for decades. Not only was he tremendously talented, but he was also generous, kind, and brave."