Beyoncé and joined in a surprise performance of Williams' single, "Say Yes," which also netted an award for music video of the year.
Campbell was the night's big winner at the Orleans Arena in Las Vegas, winning artist of the year as well as female vocalist and CD of the year for "Help."
Tiffany Joy McGhee's "Amazing" was named song of the year, and Deitrick Haddon took male vocalist honors. Haddon's LXW also won in the contemporary choir category.
The awards will be broadcast April 5 on the TV One network.